五百零四章 氨基丙醇加氢(1 / 1)

原因找到了,可这么多批的不合格品,至少得拿比旋度很好的四产品来混和,乙酰氧基丙酰氯得全部重新制备。碘帕醇一批的生产周期就得一个月,虽然是连续生产,四批下来,化了二个多月的时间,加上混和与后处理等等的工作,扫尾结束,已近过年。

总算处理完毕了,整个财务核算的结果,总产值900多万,生产成本也900多万,刚好持平,把损失的都补回来了,王近之满怀欣喜地把报告写好交给吴总与胡总。

胡总看到报告后的第一反应却是:“怎么,这个产品搞下来一分钱也没赚,这三个月你们几个在干些什么?”

满以为能听到表扬的,谁知听到这话,王近之火气涌起上来了说道:“人家挖了个坑,已经亏了,几百万产品得报废了,我给填平的好不好?”

“这是你们技术部门内部的事,你们自个内部协商去。”胡老大甩出这样一句话,结束了本次交流。

年终结算,开发一部的年终奖总和只是意思一下发了六千,部门这么多人呢,怎么分?王近之有些失望。

2011年的春假阴雨绵绵,天阴阴的有如王近之的心情,开工后能干什么呢?自个不要紧,不能让跟着自个的实验员无活干而寒心。王近之天天地担心着并思考这事,度日如年,总算熬到了开工。

第一天,吴总急急忙忙地来到开发一部办公室说:“公司有个紧急任务,左氧成本太高,谷老师查阅到一篇文献,可以通过对L-丙氨酸酯加氢得到L-氨基丙醇,达到降低侧链成本的目的,你在轻旋从事的就是加氢,这事你给在尽可能短的时间内给拿下。”

目前市面上的L-氨基丙醇多是硼氢化钠还原而成,这部分的成本大约八到十一万元每吨,随硼氢化钠的价格而波动,如加氢还原能成功,L-氨基丙醇价格能下降近一半,对左氧价格下降确有较大帮助。王近之接过资料看了一下,用的是钌碳或铑碳,加氢压力20MPa,这条件有些苛刻,所喜的是文件资料是一篇德文文献上发表的。德文文献以严肃著称,一般情况下,文章的可信性极高,按它的要求操作,基本上可以还原出结果。只是钌碳与铑碳的价格高得吓人,一般是钯碳的几倍到十倍。

加氢活性最好的催化剂自然是铑碳,可这价格实在离谱,5%的就得八万一千克,小样市场报价一千元一克,资料报道的比例又高,得溶液量的10%,应当是用大量催化剂在高压下强制加氢的,500L小试加氢釜以装料300L计,得30克,即催化剂三万元。钌碳是铑碳的30%价格,也得一万元。

这不太好搞,万一加氢不成功,来个十批八批的,小试成本都得几十万,并且,催化剂在成本中占比这么大,套用次数直接决定产品成本,而做出催化剂寿命更是一件吃力不讨好的事。

经过二十天的小试,加氢条件出来了,用较便宜的钌碳,催化剂用量得10%左右,评估结果,一个2000 L的加氢釜,一次投入钌碳得150千克,也即360万元,而产出的L-氨基丙醇只有600多千克。

“氢气的成本可以忽略不计,催化剂套用次数与再生是整个生产成本的关键所在,套用一百次才能与目前的硼氢化钠成本持平,如果试生产的话,高压加氢,在安全管理上也是个问题,公司的氢化压力不超过1MPa,而它得达到10MPa以上,并且一次性催化剂投入就是个天文数字。”向吴总汇报这个小试结果时,王近之感到底气不足,自觉地放低了声音。

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